Research also indicates that laughter enhances oxygen intake, which stimulates the heart, lungs, and muscles and increases the production of natural killer cells, a type of lymphocyte that attacks viruses and tumor cells. In a very real sense, laughter can be seen as a natural, non-invasive medicine that can significantly improve both our physical and mental health.
https://www.mxarticle.com/joyous-laughter-nyt/