The Zambia cholera vaccines market is primarily driven by the rising prevalence of cholera in the country. Cholera vaccines help in preventing the spread of cholera by building immunity against the disease. These vaccines provide cross-protective immunity against the Vibrio cholerae bacteria which causes cholera. The cholera disease is endemic in Zambia and is a major public health issue. It is spread through consumption of contaminated water and food. Cholera vaccines play a key role in protecting at-risk population groups such as UN peacekeepers, travelers to cholera-affected regions and refugees.

The Global Zambia Cholera Vaccines Market is estimated to be valued at US$1.47 million in 2024 and is expected to exhibit a CAGR of 14% over the forecast period 2024 to 2031.

Key Takeaways

Key players operating in the Zambia cholera vaccines market are Biovac Inc., Valneva SE., EMERGENT, Astellas Pharma Inc, Sanofi, EUBIOLOGICS CO., LTD,Johnson & Johnson Services Inc., Celldex Therapeutics. The key players are focused on developing improved oral cholera vaccines to widen the protective efficacy and durability of protection.

The demand for Zambia Cholera Vaccines Market Demand is projected to grow significantly during the forecast period owing to rising incidence of cholera outbreaks in Zambia. As per WHO, between 2017 to 2021, Zambia reported over 3000 cholera cases annually. In 2021 alone, over 4500 suspected cholera cases were reported across 7 provinces of Zambia.

Technological advancements include development of improved oral cholera vaccines with novel adjuvants, delivery systems and antigen combinations. Some examples include EpiVax's cholera vaccine candidate EPV-Chol01, oral recombinant live attenuated CVD 103-HgR vaccine and Shanchol vaccine developed by Shantha Biotechnics Ltd. Ease of administration of oral vaccines over injectable ones is also fueling their demand.

Market Trends

Growing adoption of oral cholera vaccines - Oral cholera vaccines provide logistic advantages compared to injectable cholera vaccines due to ease of administration without requiring trained healthcare staff. This is boosting the adoption of oral cholera vaccines globally.

Increased focus on immunization programs - Both national and international organizations are focusing on strengthening immunization programs to control cholera outbreaks in disease-endemic countries like Zambia. Proper implementation of immunization plans can significantly reduce disease burden.

Market Opportunities

Emerging economies in sub-Saharan Africa - Sub-Saharan Africa registers highest cholera disease burden worldwide providing scope for vaccines. Zambia being a cost-effective vaccine production hub can potentially manufacture and supply vaccines in the region.

Introduction of combination vaccines - Combination vaccines providing protection against both cholera and other related diarrheal diseases can improve compliance and maximize health benefits. This presents numerous growth opportunities.

Impact of COVID-19 on Zambia Cholera Vaccines Market Growth

The COVID-19 pandemic has adversely impacted the growth of the Zambia cholera vaccines market. During the initial lockdown phases imposed across countries to contain the spread of the virus, the production and supply chain of cholera vaccines were disrupted. This led to shortages and delays in vaccine procurement. The focus of healthcare resources also shifted towards treatment of COVID-19 patients, which reduced vaccination programs for other diseases like cholera. However, some countries continued mass vaccination campaigns for high-risk groups to prevent outbreaks. With resumption of regular vaccination programs post lockdowns, the market is recovering slowly. But the threat of future COVID-19 waves can affect the market again. Companies will need to enhance production capacities and build resilient supply networks to overcome such challenges in future. Diversifying sourcing and increasing local manufacturing can help address potential disruptions.

Geographical Regions with High Market Concentration in Zambia

In terms of value, the Zambia cholera vaccines market is highly concentrated in urban areas like Lusaka and Kitwe. These densely populated cities frequently report cholera outbreaks due to issues like unsanitary living conditions and contaminated water supply. They account for over 60% of the country's total vaccine procurement. Other regions with high demand include the copperbelt province due to its mining towns and crowded living sites lacking basic sanitation. Efforts to improve water and hygiene infrastructure can help tackle the disease burden in these hotspots and reduce their vaccine requirements in the long run.

Fastest Growing Region in the Zambia Cholera Vaccines Market

The southern province of Zambia is poised to be the fastest growing region for the cholera vaccines market during the forecast period. This is because development initiatives are ongoing to expand access to clean water and strengthen public health facilities in the rural districts of Namwala, Mazabuka and Monze. Successful implementation can boost vaccination coverage and curb rising cholera incidence reported from these areas in recent years. Additionally, improved connectivity and decentralized procurement may aid faster vaccine deployment to remote communities. These factors are likely to drive strong market growth in southern Zambia compared to other established regions.

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