Based on extensive experience in the lncRNA field, IntegrateRNA provides customers with a comprehensive lncRNA pull-down service, from the initial experimental design to the identification of the last interacting molecules. Our experienced scientists and advanced technologies enable us to provide consistent and high-quality data in a cost-effective manner.

Studies have shown that lncRNA has a conserved secondary structure, can interact with proteins, DNA and RNA, and participates in a variety of biological processes. With the development of high-throughput sequencing technology, more and more lncRNAs have been annotated, but the functions of most lncRNAs are still unclear. Therefore, the study of lncRNAs is a very broad unknown field and has great scientific value. RNA pull-down technology has played a vital role in the validation of lncRNA biology.

High-throughput screening for the interacting proteins of lncRNA is convenient by pull-down combined with LC-MS. IntegrateRNA utilizes LC-MS to identify captured protein complexes, and then screen specificity Interacting proteins with the target lncRNA.