dsRNA Synthesis Services - Creative Biogene IntegrateRNA
Double-strand RNA (dsRNA) is a signal for gene-specific silencing of expression in a number of organisms. It triggers different types of gene silencing that are collectively referred to as RNA silencing or RNA interference (RNAi). During RNAi, the dsRNA is recognized by DICER-like enzymes, which cleaves the molecule into a series of 21-23 bp double-stranded small RNAs (siRNAs). The siRNAs are then incorporated into an RNA-induced silencing complex (RISC), which mediates the degradation of mRNAs with sequences fully complementary to the siRNA. In another reaction, occurring in the nucleus, siRNAs formed from repeat element transcripts and incorporated into the RNAi-induced transcriptional silencing (RITS) complex may guide chromatin modification and silencing.<a href="https://integraterna.creative-biogene.com/dsrna-synthesis-services.html">double stranded rna synthesis</a>
